Advisory Board

DR. (MRS.) Evelyn Yayra Afua Bonney
Email : Ebonney@noguchi.ug.edu.gh
Phone :+233-302-501178/9
Fax : +233-302-502128/513202
Department : VIROLOGY
 
 
Biography

Dr. Mrs. Evelyn Yayra Afua Bonney holds a BSc. Honours in Biochemistry and Nutrition, an MPhil in Biochemistry and a PhD in Biochemistry; all from the University of Ghana.

She is a recipient of HIV Research Trust Scholarship, from the HIV Research Trust, UK in 2007. This award sponsored her research training visit to the Department of Viral Pathogenesis, National Centre for Microbiology, Institute of Health Carlos III, Spain, to acquire the skills and techniques needed to complete her PhD.
Her PhD research focussed on determination of drug resistance mutations in HIV patients on antiretroviral therapy (ART) in Ghana. The study showed that patients on ART in Ghana may not be deriving optimal benefit from treatment due to the limited markers being used for monitoring and recommended that viral load testing be implemented and resistance testing should be done before a switch in regimen.

She has teaching responsibilities for both undergraduate and postgraduate students in the University of Ghana and these include:
1)  Guest Lecturer, Biochemistry of Viruses and Molecular Epidemiology, Department of Biochemistry, Cell and Molecular Biology
2)  Instructor, MA HIV/AIDS Management, Department of Adult Education and Human Resource Studies, School of Continuing and Distance Education, College of Education

As a Postdoctoral Fellow, she is investigating the impact of host factors, such as APOBEC3/G and variations in mitochondrial DNA, on HIV infection, disease progression and response to antiretroviral therapy.

 
 
Administrative Role

1. Laboratory Supervisor of HIV Genotyping Lab
2. Quality Focal Person for Virology Department
 
Research Interest
  1. Host factors/proteins influencing viral infections
  2. Antiviral therapy,  susceptibility and resistance
  3. Genetic variability of HIV, HTLV-1, HPV and Influenza viruses;
  4. Co-infections of HIV and other infections among key population
 
Projects
Impact of host factors on HIV infection, disease progression and response to antiretroviral therapy. Role: Principal Investigator

 
Articles in Peer-Reviewed Biomedical Journals

1. Brandful JAM, Bonney EY, Asmah RH, Apea-Kubi KA. Onchogenic Human Papillomavirus (HPV) in women in Ghana, Journal of Cancer Research and Experimental Onchology 2014, 6 (4): 31-38

2. Barnor JS, Yamamoto N, Brandful JAM, Ampofo W, Bonney JHK, Bonney E, Odoom JK, Aidoo S, Alale M, Ntim NA, Amoah YO, Ofori SB, Ndzinu J, Aziati ID, Addo NA, Nyarko A, Ido E, Ishikawa K, Yamaoka S. Establishment of In-House Quantitative Real-Time RT-PCR Assay for HIV-1 Viral Load Measurement: Application to Evaluate Efficacy of ART in Ghanaian Patients in an Urban Setting. J AIDS Clin Res 2014, 5: 305

3. Oliver Barry, Jonathan Powell, Lorna Renner, Evelyn Y Bonney, Meghan Prin, William Ampofo, Jonas Kusah, Bamenla Goka, Kwamena WC Sagoe, Veronika Shabanova and Elijah Paintsil, Effectiveness of first-line antiretroviral therapy and correlates of longitudinal changes in CD4 and viral load among HIV-infected children in Ghana. BMC Infectious Diseases 2013, 13:476-486

4. Evelyn Yayra Bonney, Nii Akwei Addo, Nana Afia Asante Ntim, Frederick Addo-Yobo, Philip Bondzie, Ken-Edwin Aryee, Jacob Barnor, James Brandful, Veronica Bekoe, Sally-Ann Ohene and William Ampofo, Low level of transmitted HIV Drug Resistance at two HIV care centres in Ghana: a threshold survey, Ghana Medical Journal  2013, 47 (2): 82-86

5. Bonney EY, Sackey ST and Brandful JAM. Laboratory Diagnosis of Dual HIV-1/HIV-2 Infections in HIV Seropositive Ghanaians East African Medical Journal 2008, 85 (12): 517-523

6. Delgado, E, Ampofo, WK, Sierra, M, Torpey, K, Perez-A´lvarez, L, Bonney, EY, Mukadi, YD, Lartey, M, Nyarko, C, Amenyah, RN, Thomson, MM. and Rafael Na´ jera. High Prevalence of Unique Recombinant Forms of HIV-1 in Ghana: Molecular Epidemiology from an Antiretroviral Resistance Study, J Acquir Immune Defic Syndr 2008, 48 (5): 599-606

7. Kinomoto, M, Appiah-Opong R, Brandful, J, Yokoyama, M, Nii-Trebi, N, Ugly-Kwame, E, Sato, H, Ofori-Adjei, D, Kurata, T, Barre-Sinoussi, F, Sata, T. and Tokunaga, K. (2005). HIV-1 Proteases from Drug-Naïve West African Patience Are Differentially Less Susceptible to Protease Inhibitors, Clinical Infectious Diseases2005, 41: 243-51
 
Books

Bonney Evelyn Yayra A. (2013), Drug Resistance Mutations in HIV Patients on Antiretroviral Therapy in Ghana, A PhD thesis submitted to the University of Ghana, School of graduate Studies in partial fulfillment of the requirements for the award of a Doctor of Philosophy degree in Biochemistry.

Book Chapter (s)
William K. Ampofo and Evelyn Y. Bonney (2014), Investigations to support the prevention and management of HIV in Ghana, University of Ghana Reader Series Volume 2, Sub-Saharan Publishers, pages 220-229

She contributed to Chapter 10 (on Viruses) of the book “Molecules of LIFE; Structure and Function at a glance” by Dr. J. P. Adjimani (2008) published by Beno Publications, Accra.
 
 
Dr. Kwadwo Asamoah Kusi
 DR. Evelyn Yayra Afua Bonney Kingsley Badu
     
Dr Aminata Colle LO Samuel Asamoah Sakyi Dr. Jewelna Akorli
(nee Osei-Poku)
     
Dr Patrick Valere Tsouh Fokou
 Dr. Patrick Kobina Arthur Dr. Joseph Mwanzia Nguta
     
 
Dr Edward Maina Protus Arrey Tarkang